Anaesthesia’s Special Supplement on Transfusion, thrombosis and management of bleeding is now online

Transfusion, thrombosis and management of bleeding is the subject of a special supplement in the January 2015 issue of Anaesthesia, the journal of the Association of Anaesthetists of Great Britain and Ireland.

The Supplement is the result of collaboration between anaesthetists, haematologists, surgeons and other associated experts and it brings together state-of-the-art research and recommendations on a comprehensive range of blood-related issues.  

Its publication comes hard on the heels of Patient Blood Management, a multidisciplinary, evidence-based approach that aims to improve patient care and reduce the inappropriate use of blood products. Launched by the National Blood Transfusion Committee in June 2014, with the support of NHS England and the Department of Health, the initiative aims to optimise erythropoiesis, employ restrictive transfusion thresholds and minimise blood loss and allogeneic transfusion.

Anaesthesia’s Editor-in-Chief Dr Steve Yentis says: “Over the last decade, there has been a massive expansion of interest in blood conservation, testing of coagulation profiles and the use of haemostatic agents. Many have challenged the elective transfusion of red cells and other blood products and one of this supplement’s major themes is the effort to reduce blood transfusions. This Supplement also follows the publication of the latest National Institute for Health and Care Excellence’s Diagnostics Guidance on visco-elastometric point-of-care testing.”

The Supplement is now online and will be mailed out with hard copies of the January issue to all subscribers. It can be accessed for free online here:

The papers in the supplement cover:

  • Editorial: Blood – the most important humor?
  • Modern banking, collection, compatibility testing and storage of blood and blood components
  • Evidence and triggers for the transfusion of blood and blood products
  • Pre-operative anaemia
  • The pathophysiology and consequences of red blood cell storage
  • Red cell transfusion and the immune system
  • The current place of aprotinin in the management of bleeding
  • The current place of tranexamic acid in the management of bleeding
  • Practical management of major blood loss
  • Management of peri-operative anti-thrombotic therapy
  • Point-of-care monitoring of haemostasis
  • Laboratory monitoring of haemostasis
  • Haemostatic management of obstetric haemorrhage
  • Haemostatic management of cardiac surgical haemorrhage
  • The pathogenesis of traumatic coagulopathy
  • Management of traumatic haemorrhage – the European perspective
  • Management of traumatic haemorrhage – the US perspective
  • Surgery in patients with inherited bleeding disorders
  • The management of abnormal haemostasis in intensive care

Members keen to develop their expertise in this area will also be interested to know that there are still places available on the AAGBI’s two-day seminar on Bleeding, clotting and haemorrhage, which will be held near our Central London headquarters from 11 to 12 December. More details can be found here:   

Other useful links

The Patient Blood Management strategy can be found at:

The NICE guidance on visco-elastometric point-of-care- testing can be accessed at:

The Anaesthesia homepage, containing all content going back to 1946, much of it freely available, can be found at:

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